REDCap Variable List

Complete variable list from the Terlipressin Database REDCap Code Book (PID: 43500). The database contains 18 instruments with 1500+ fields. Treatment day instruments (Day 0–13) share identical structure and are documented once below.

Demographics

#	Variable	Field Label	Type	Values / Unit
1	subjectid	Subject ID	text	e.g. BCM-001
4	admit_date	Admit date	date	Required
5	admit_admitservice	Admitting Service	categorical	1 = Medicine, 2 = ICU, 3 = Primary Liver Service, 4 = Surgical, 5 = Other
6	admit_admitroute	Location patient was admitted from	categorical	1 = Emergency Room, 2 = Transfer from outside hospital, 3 = Direct admission
7	date_birth	Date of birth	date	Required
8	age	Age	calculated	rounddown(datediff(date_birth, admit_date, "y"))
9	sex_male	Sex	categorical	1 = Male, 0 = Female
10	race	Race	categorical	1 = White, 2 = Black, 3 = Asian, 4 = Other
11	hispanic	Hispanic	categorical	1 = Hispanic or Latino, 0 = Not Hispanic or Latino
12	insurance_type	Type of insurance	categorical	1 = Medicare, 2 = Medicaid, 3 = Private, 4 = Self pay, 5 = Other
14	cirrhosis_etiology	Cirrhosis etiology	categorical	1 = Alcohol, 2 = MASH (NASH), 3 = HCV, 4 = HCV+Alcohol, 5 = MetALD (Alcohol + MASH), 6 = Other
16	etoh_hepatitis	Does patient have alcohol associated hepatitis?	binary	1 = Yes, 0 = No
17	admit_reason	Reason(s) for admission	checkbox	1 = Overt HE, 2 = Portal hypertension related bleed, 3 = Ascites/Anasarca, 4 = Infection, 5 = AKI, 6 = Other, 7 = Liver-unrelated

Medical History

Comorbidities

#	Variable	Field Label	Type	Values
20	htn_medical_hx	History of hypertension?	categorical	0 = No, 1 = Yes
21	dm_medical_hx	History of diabetes?	categorical	0 = No, 1 = Yes
22	ckd_medical_hx	History of chronic kidney disease?	categorical	0 = No, 1 = Yes
23	cad_medical_hx	History of coronary artery disease?	binary	1 = Yes, 0 = No

Pre-Admission / Home Medications

#	Variable	Field Label	Type	Values
24	nsbb_preadmission	Non-selective beta-blocker?	categorical	0 = No, 1 = Yes
25	nsbb_type_preadmission	Type of non-selective beta blocker?	categorical	1 = Propranolol, 2 = Carvedilol, 3 = Nadolol, 4 = Other
26	nsbb_dose_preadmission	Total dose per day of non-selective beta blocker total dose (mg)	number	0–160
27	ace_arb_preadmission	ACE-inhibitor or ARB?	categorical	0 = No, 1 = Yes
28	nsaid_preadmission	NSAID use?	categorical	0 = No, 1 = Yes
29	diuretics_preadmission	Loop diuretic?	categorical	0 = No, 1 = Yes
30	potsp_diuretic_preadmission	Potassium sparing diuretic?	binary	1 = Yes, 0 = No
31	sbp_ppx_preadmission	Spontaneous bacterial peritonitis (SBP) prophylaxis?	categorical	0 = None, 1 = Ciprofloxacin, 2 = Sulfamethoxazole/trimethoprim, 3 = Other
32	lactulose_preadmission	Lactulose?	categorical	0 = No, 1 = Yes
33	rifaximin_preadmission	Rifaximin?	categorical	0 = No, 1 = Yes
34	mido_preadmission	Midodrine	binary	1 = Yes, 0 = No
35	mido_dose_preadmission	Total dose of midodrine per day (mg)	text

History of Previous Cirrhosis Complications

#	Variable	Field Label	Type	Values
36	ascites_previous_comp	Ascites?	binary	1 = Yes, 0 = No
37	refascites_previous_comp	Is ascites refractory? Failed maximum doses of diuretics or Diuretic intolerant or Requiring paracentesis >1x within 2 weeks	binary	1 = Yes, 0 = No
38	he_previous_comp	Hepatic encephalopathy?	binary	1 = Yes, 0 = No
39	sbp_previous_comp	Spontaneous bacterial peritonitis (SBP)?	binary	1 = Yes, 0 = No
40	nonsbp_previous_comp	Non-SBP infections (within previous 90 days)?	binary	1 = Yes, 0 = No
41	phtn_bleed_previous_comp	Portal hypertension related bleed?	binary	1 = Yes, 0 = No
42	hcc_previous_comp	Hepatocellular carcinoma?	binary	1 = Yes, 0 = No
43	tips_previous_comp	History of TIPS?	categorical	0 = No, 1 = Yes

Baseline Creatinine

#	Variable	Field Label	Type	Values / Unit
44	baseline_scr	Baseline creatinine (creatinine value within three months before hospitalization; if more than one value, use closest to admission; if no baseline, use admission creatinine)	number	mg/dL, 0.2–10, Required
46	baseline_scr_days_to_admit	Days from baseline serum creatinine to admission date	calculated
47	baseline_scr_outpt	Was baseline creatinine an outpatient value?	binary	1 = Yes, 0 = No
48	baseline_scr_120to365	Is there an outpatient serum creatinine value 120-365 days from baseline serum creatinine?	binary	1 = Yes, 0 = No
49	baseline_scr_120to365_value	Outpatient serum creatinine value 120-365 days from baseline serum creatinine value (mg/dL)	text	mg/dL
50	aki_previous_90days	Known AKI within 90-days of admission?	categorical	0 = No, 1 = Yes
51	aki_events_previous90days	How many known AKI events in the previous 90 days?	text

Labs within 72 Hours of Admission

Within 72 hours of admission, use the closest value to admission date.

#	Variable	Field Label	Type	Unit
58	scr_admit	Serum creatinine	number	mg/dL
60	cystatinc_admit	Cystatin C	number	mg/L
62	tbili_admit	Total bilirubin	number	mg/dL
64	inr_admit	INR	number	–
66	sodium_admit	Serum sodium	number	mmol/L
68	albumin_admit	Admit albumin	number	g/dL
70	lactate_admit	Admit Lactate	number	mmol/L
71	hegrade_admit	HE grade at admission	categorical	0 = None, 1 = Grade 1, 2 = Grade 2, 3 = Grade 3, 4 = Grade 4
72	admit_ascites	Ascites severity at admission	categorical	1 = Absent, 2 = Slight/Moderate, 3 = Large/Tense

AKI Details

Details of Initial AKI Diagnosis

#	Variable	Field Label	Type	Values
74	aki_date	Date when ICA AKI criteria met (increase in sCr ≥0.3 mg/dl within 48 hours; or a percentage increase in sCr ≥50% from baseline)	date	Required
75	days_admit_to_aki	Days from admission to ICA AKI event	calculated
76	aki_precipitant	Precipitant of AKI	checkbox	1 = Non-bleeding volume loss/excessive diuretic use, 2 = SBP, 3 = Non-SBP infection, 4 = GI bleed, 5 = Nephrotoxic drugs, 6 = Other, 7 = No identifiable precipitant
77	aki_precipitant_nsbpinf	If precipitant was non-SBP infection, what was it?	categorical	1 = Pneumonia, 2 = UTI, 3 = Bacteremia, 4 = Other
52	transfer_aki	Was the patient transferred from another hospital with an AKI?	categorical	0 = No, 1 = Yes
54	transfer_aki_days_toadmit	Days from transfer to admission date	calculated

Vital Signs at Time of Initial AKI

#	Variable	Field Label	Type	Unit
80	aki_weight	Body weight	number	kg (30–150)
81	aki_height	Height	text	cm
82	aki_hr	Heart Rate (pick the highest value of day of AKI diagnosis)	number	BPM
83	aki_sbp	Systolic BP (pick the lowest value of day of AKI diagnosis)	number	mmHg
84	aki_dbp	Diastolic BP (pick the value associated with systolic BP above)	number	mmHg
85	aki_map	MAP	calculated	mmHg; round((1/3)*SBP + (2/3)*DBP, 2)
86	aki_spo2	SpO2 (pick the lowest value of day of AKI diagnosis)	number	%
87	aki_pao2	PaO2 (convert lowest value of SpO2 to PaO2)	number	mmHg (40–150)
88	fio2_aki	FiO2 (pick value associated with SpO2; room air is 0.21, add 0.04 for every L of nasal canula)	number	% (0–100)

Labs at Time of Initial AKI

Pick worst value on day of AKI as specified.

#	Variable	Field Label	Type	Unit
91	sodium_aki	Serum sodium (pick the lowest value)	number	mmol/L
93	potassium_aki	Serum potassium (pick the highest value)	number	mmol/L
95	scr_aki	Serum creatinine (pick the highest value)	number	mg/dL, Required
97	cystatinc_aki	Cystatin C (pick the highest value)	number	mg/L
99	bun_aki	BUN (pick the highest value)	number	mg/dL
101	tbili_aki	Total bilirubin (pick the highest value)	number	mg/dL
103	albumin_aki	Albumin (pick the lowest value)	number	g/dL
105	inr_aki	INR (pick the highest value)	number	–
107	wbc_aki	Total WBC (pick the highest value)	number	10^9/L
109	plt_aki	Platelet count (pick the lowest value)	number	10^9/L

Details for Prognosis Scores at Time of Initial AKI

#	Variable	Field Label	Type	Values
110	he_aki	HE grade on day of AKI	categorical	0 = None, 1 = Grade 1 (minimal change in consciousness), 2 = Grade 2 (gross disorientation, drowsiness, asterixis), 3 = Grade 3 (marked confusion, sleeping most of the time but arousable), 4 = Grade 4 (comatose)
111	ascites_aki	Ascites severity on day of AKI	categorical	1 = Absent, 2 = Slight/Moderate, 3 = Large/Tense
112	rrt_aki	Was the patient on renal replacement therapy on day of AKI?	categorical	0 = No, 1 = Yes
113	mv_aki	Was the patient intubated on day of AKI?	categorical	0 = No, 1 = Yes
116	pressors_aki	Was the patient on vasopressors on day of AKI (e.g., norepinephrine, vasopressin)? Not including terlipressin, midodrine/octreotide.	categorical	0 = No, 1 = Yes

Cardio-Pulmonary History

Pulmonary and Cardiac Parameters

#	Variable	Field Label	Type	Values / Unit
118	chest_imaging	Chest imaging obtained prior to terlipressin initiation?	binary	1 = Yes, 0 = No
119	chest_imaging_pulmedema	Presence of pulmonary edema/congestion?	binary	1 = Yes, 0 = No
120	chest_imaging_effusion	Presence of pleural effusion?	binary	1 = Yes, 0 = No
121	ecg	ECG obtained prior to terlipressin initiation?	binary	1 = Yes, 0 = No
124	ecg_qtc	Corrected QTC on ECG	number
125	echo	Echocardiogram within 1 year of terlipressin initiation?	binary	1 = Yes, 0 = No
127	days_to_echo	Days from admission to echocardiogram	calculated
129	echo_ef	LV ejection fraction (take average if range is reported)	number	%
131	echo_lateral_e	Lateral e’ velocity	number	cm/sec
133	echo_trpeak	Peak tricuspid regurgitation velocity	number	cm/sec
135	echo_gls	Average global longitudinal strain	number	%
137	echo_earatio	Mitral E/A ratio	number
139	echo_eeratio	E/e’ ratio	number
141	echo_rvsp	Right ventricular systolic pressure	number	mmHg
143	echo_pasp	Pulmonary artery systolic pressure	number	mmHg
145	echo_lavi	Left atrial volume index (LAVI)	number	mL/m2
147	echo_tr	Tricuspid regurgitation (TR) velocity	number	m/sec

HRS Diagnosis Details

HRS-AKI Diagnosis Details

#	Variable	Field Label	Type	Values
149	hrs_aki_criteria	Was ICA HRS-AKI criteria met? (Select all criteria that were met)	checkbox	1 = Cirrhosis with ascites, 2 = Diagnosis of AKI according to ICA-AKI criteria, 3 = No response after 2 consecutive days of diuretic withdrawal and plasma volume expansion with albumin (1 g per kg of body weight), 4 = Absence of shock, 5 = No current or recent use of nephrotoxic drugs, 6 = Absence of proteinuria (>500 mg/day), 7 = Absence of microhematuria (>50 RBCs per HPF), 8 = Normal findings on kidney ultrasonography

Volume Resuscitation Prior to Terlipressin

#	Variable	Field Label	Type	Values
150	albumin_before_terli	Was albumin given from time of admission to terlipressin initiation?	binary	1 = Yes, 0 = No
151	totalalbumin_before_terli	Total albumin given from time of admission to terlipressin initiation (grams)	number	grams
152	albvolume_before_terli	Total volume of albumin given from time of admission to terlipressin initiation (mL)	number	mL
153	crystalloid_before_terli	Was crystalloids (normal saline, lactated ringers) given from time of admission to terlipressin initiation?	categorical	0 = No, 1 = Yes
155	saline_vol_before_terli	Total volume of normal saline given from time of admission to terlipressin initiation (mL)	number	mL
156	lr_volume_before_terli	Total volume of lactated ringers given from time of admission to terlipressin initiation (mL)	number	mL
158	prbc_trans_before_terli	Was packed red blood cell transfusion given from time of admission to terlipressin initiation?	categorical	0 = No, 1 = Yes
159	prbc_qaunt_before_terli	How many units of packed red blood cells given from time of admission to terlipressin initiation (units)	number	units
160	totalvolume_before_terli	Total volume (input) given from time of admission to terlipressin initiation (mL)	text	mL
161	total_uo_before_terli	Total urine output (mL) from time of admission to terlipressin initiation	text	mL

Medications Prior to Terlipressin

#	Variable	Field Label	Type	Values
162	nsbb_before_terli	Non-selective beta blocker use from time of admission to terlipressin initiation?	categorical	1 = Withdrawn, 2 = Tapered, 3 = Continued, 4 = Not applicable
164	mido_before_terli	Midodrine given from time of admission to terlipressin initiation?	binary	1 = Yes, 0 = No
166	days_first_mido_before_terli	Days from admission to first dose of midodrine	calculated
168	days_total_mido_before_terli	Days from admission to last dose of midodrine before terlipressin initiation	calculated
169	mido_maxdose_before_terli	What was the maximum total dose of midodrine given in a day (mg)	text	mg
170	oct_before_terli	Octreotide given from time of admission to terlipressin initiation?	binary	1 = Yes, 0 = No
172	days_first_oct_before_terli	Days from admission to first dose of octreotide	calculated
174	days_total_oct_before_terli	Days from admission to last dose of octreotide before terlipressin initiation	calculated
175	oct_maxdose_before_terli	What was the maximum total dose of octreotide given in a day (mcg)	text	mcg
176	ne_before_terli	Norepinephrine given from time of admission to terlipressin initiation?	binary	1 = Yes, 0 = No
178	days_first_ne_before_terli	Days from admission to first dose of norepinephrine	calculated
180	days_total_ne_before_terli	Days from admission to last dose of norepinephrine before terlipressin initiation	calculated
181	norepi_dose_before_terli	What was the maximum total dose of norepinephrine given in a day (mcg)	text	mcg

Consultation Information

#	Variable	Field Label	Type	Values
182	gihep_consult	GI/Hep consultation	binary	1 = Yes, 0 = No
184	days_to_gihep_consult	Days from admission to GI/Hep consultation	calculated
185	neph_consult	Nephrology consultation	binary	1 = Yes, 0 = No
187	days_to_neph_consult	Days from admission to nephrology consultation	calculated
188	pall_consult	Palliative care consultation	binary	1 = Yes, 0 = No
190	days_to_pall_consult	Days from admission to palliative care consultation	calculated
191	code_status	Code status	categorical	1 = Full code, 2 = DNR

Urinary Indices

#	Variable	Field Label	Type	Unit
192	ua_hrs	Urine analysis available?	categorical	0 = No, 1 = Yes
195	ua_na_hrs	Urine sodium available?	binary	1 = Yes, 0 = No
198	ua_na_value_hrs	Urine sodium (if <10, enter 9; if <20, enter 19)	number	mmol/L
199	sna_value_day_of_ua_na_hrs	Serum sodium on day of urine sodium (if not collected on day of, use closest value within 24 hours)	text	mmol/L
200	ua_cr_hrs	Urine creatinine available?	binary	1 = Yes, 0 = No
203	ua_cr_value_hrs	Urine creatinine	number	mg/dL
204	scr_value_day_of_ua_cr_hrs	Serum creatinine on day of urine creatinine (if not collected on day of, use closest value within 24 hours)	text	mg/dL
205	ua_urea_hrs	Urine urea nitrogen available?	binary	1 = Yes, 0 = No
208	ua_urea_value_hrs	Urine urea nitrogen	number	mg/dL
210	fena_hrs	FeNa (%)	calculated
211	feurea_hrs	FEUrea (%)	calculated
212	ungal_hrs	Urine NGAL available?	binary	1 = Yes, 0 = No
215	ungal_value_hrs	Urine NGAL	number	ng/mL
216	ua_rbc_hrs	Number of urine rbcs per high power field on urine analysis	number	per HPF
217	uaprotein_hrs	Amount of protein in urine with spot check or 24-hour urine collection (spot check: mg protein/g Cr, or total mg for 24hr collection)	number	mg
218	ua_granularcasts_hrs	Presence of urine granular casts on urine analysis?	binary	1 = Yes, 0 = No
219	ua_epi_cells_hrs	Presence of urine tubular epithelial cells on urine analysis?	binary	1 = Yes, 0 = No

Terlipressin Treatment Days 0–13

Each treatment day (Day 0 through Day 13) contains identical fields. Variables are suffixed _day0 through _day13. Below uses N as placeholder.

Terlipressin Treatment

Variable Pattern	Field Label	Type	Values
terli_date_dayN	Day N date	date
days_to_terli_initiation_dayN	Days from admission to day N of terlipressin	calculated
discont_terli_dayN	Was terlipressin discontinued?	binary	1 = Yes, 0 = No
discont_reason_terli_dayN	What was the reason of discontinuation?	categorical	1 = Adverse Effect (abdominal pain, nausea, diarrhea, volume overload, bradycardia), 2 = Achieved HRS Reversal (serum creatinine < or = 1.5 mg/dL), 3 = Worsening Kidney Function or Requiring Renal Replacement Therapy, 4 = Death, 5 = Transitioned to Hospice, 6 = Further Decompensation Requiring ICU care, 7 = Respiratory Failure, 8 = Ischemic Related Event (skin discoloration, cyanosis, organ ischemia), 9 = Other

Adverse Events (shown if discontinued due to adverse effect)

Variable Pattern	Field Label	Type	Values
terli_ae_abdpain_dayN	Abdominal pain	binary	1 = Yes, 0 = No
terli_ae_nausea_dayN	Nausea	binary	1 = Yes, 0 = No
terli_ae_diarrhea_dayN	Diarrhea	binary	1 = Yes, 0 = No
terli_ae_volover_dayN	Volume Overload	binary	1 = Yes, 0 = No
terli_ae_brady_dayN	Bradycardia	binary	1 = Yes, 0 = No
terli_rrtmod_dayN	What was the modality of renal replacement therapy	categorical	0 = Not applicable, 1 = Intermittent, 2 = Continuous
terli_other_dayN	If other, what was the reason	text

Dosing

Variable Pattern	Field Label	Type	Values
terli_route_day0	Route of terlipressin initiation? (Day 0 only)	categorical	1 = Bolus, 2 = Continuous
initial_bolusdose_terli_day0	If bolus, initial dose? (mg)	text	mg
initial_contdose_terli_day0	If continuous, initial dose? (mg)	text	mg
dosechange_terli_dayN	If no, was dose adjusted?	binary	1 = Yes, 0 = No
doseadjust_terli_dayN	What was the new dose?	text	mg
total_terli_dayN	Total terlipressin dose for day N (mg)	text	mg

Concomitant Medications (per day)

Variable Pattern	Field Label	Type	Values / Unit
albumin_terli_dayN	Albumin use?	binary	1 = Yes, 0 = No
albumintotal_terli_dayN	Total grams of albumin given for day N	text	grams
albuminvolume_terli_dayN	Total volume of albumin for day N	text	mL
mido_terli_dayN	Midodrine use while on terlipressin?	binary	1 = Yes, 0 = No
mido_dose_terli_dayN	Total dose midodrine for day N	text	mg
octreo_terli_dayN	Octreotide use while on terlipressin?	binary	1 = Yes, 0 = No
octreo_dose_terli_dayN	Total octreotide dose for day N	text	mcg
norepi_terli_dayN	Norepinephrine use while on terlipressin?	binary	1 = Yes, 0 = No
norepi_dose_terli_dayN	Total norepinephrine dose for day N	text	mcg

Vital Signs (per day, 4 time points)

Variable Pattern	Field Label	Type	Unit
tele_terli_dayN	Continuous telemetry	binary	1 = Yes, 0 = No
pulseox_terli_dayN	Continuous pulse oximetry	binary	1 = Yes, 0 = No
temp_terli_dayN	Temperature (pick closest value to terlipressin initiation time)	text	celsius
hr_terli_dayN	Heart rate (pick closest value to terlipressin initiation time)	number	BPM (40–130)
rr_terli_dayN	Respiratory rate (pick closest value to terlipressin initiation time)	text
spo2_terli_dayN	SpO2 (pick closest value to terlipressin initiation time)	number	%
pao2_terli_dayN	PaO2 (convert SpO2 closest to terlipressin initiation time to PaO2)	number	mmHg
fio2_terli_dayN	FiO2 (pick value associated with SpO2; room air is 0.21, add 0.04 for every L of nasal canula)	number	%
sbp_terli_dayN_time{0-3}	Systolic BP (time 0 = midnight/0000, time 1 = 6AM/0600, time 2 = noon/1200, time 3 = 6PM/1800)	text	mmHg
dbp_terli_dayN_time{0-3}	Diastolic BP (pick value associated with systolic BP above)	text	mmHg
map_terli_dayN_time{0-3}	MAP	calculated	mmHg; round((1/3)*SBP + (2/3)*DBP, 2)
total_volume_in_terli_dayN	Total volume input (mL)	text	mL
total_volume_out_terli_dayN	Total urine output/24 hours (mL)	text	mL

Daily Labs (per day)

Pick the value closest on day N of terlipressin.

Variable Pattern	Field Label	Type	Unit
na_terli_dayN	Serum sodium	number	mmol/L
k_terli_dayN	Serum potassium	number	mmol/L
chloride_terli_dayN	Serum chloride	text	mmol/L
bicarb_terli_dayN	Serum bicarbonate	text	mmol/L
scr_terli_dayN	Serum creatinine	number	mg/dL (Required on Day 0)
cystatinc_terli_dayN	Cystatin C	number	mg/L
bun_terli_dayN	BUN	number	mg/dL
ast_terli_dayN	AST	text	U/L
alt_terli_dayN	ALT	text	U/L
bili_terli_dayN	Total bilirubin	number	mg/dL
alb_terli_dayN	Serum albumin	number	g/dL
inr_terli_dayN	INR	number
wbc_terli_dayN	Total WBC	number	10^9/L
hgb_terli_dayN	Hemoglobin	text	g/dL
plt_terli_dayN	Platelet count	text	10^9/L

Clinical Details (per day)

Variable Pattern	Field Label	Type	Values
he_terli_dayN	HE grade day N terlipressin	categorical	0 = None, 1 = Grade 1, 2 = Grade 2, 3 = Grade 3, 4 = Grade 4
location_terli_day0	Location of terlipressin initiation? (Day 0 only)	categorical	1 = General ward, 2 = Progressive care/step down unit, 3 = ICU
diuretic_terli_dayN	Were diuretics used?	binary	1 = Yes, 0 = No
para_terli_dayN	Paracentesis?	binary	1 = Yes, 0 = No
paravolume_terli_dayN	If yes to paracentesis, how many liters?	text	liters
infection_terli_dayN	Treatment of infection?	binary	1 = Yes, 0 = No
typeinfection_terli_dayN	If yes for treatment of infection, what kind of infection?	categorical	1 = Pneumonia, 2 = UTI, 3 = Bacteremia, 4 = SBP, 5 = Other
ltlisting_terli_day0	Listed for Liver Transplantation? (Day 0 only)	categorical	0 = No, 1 = Yes, 2 = No, in evaluation

HRS-AKI Clinical Course

Creatinine Post Terlipressin Discontinuation

Variable	Field Label	Type	Unit
scr_day1_post_terli	Serum creatinine 1 day from terlipressin discontinuation	text	mg/dL
scr_day2_post_terli	Serum creatinine 2 days from terlipressin discontinuation	text	mg/dL
scr_day3_post_terli	Serum creatinine 3 days from terlipressin discontinuation	text	mg/dL
scr_day4_post_terli – scr_day14_post_terli	Serum creatinine 4–14 days from terlipressin discontinuation	text	mg/dL

HRS-AKI Reversal and HRS Recovery

#	Variable	Field Label	Type	Values
1531	hrsreversal	HRS reversal? Definition: serum creatinine < 1.5 mg/dL	binary	1 = Yes, 0 = No
1534	hrsrecovery	HRS response during hospitalization?	categorical	0 = No response, 1 = Partial (decrease in AKI stage but Scr >0.3 mg/dL above baseline), 2 = Complete (serum creatinine < 0.3 mg/dL of baseline)

Recurrent AKI

#	Variable	Field Label	Type	Values
1537	recurrentaki	Recurrent AKI during hospitalization after HRS recovery? (ADQI definition: meeting AKI criteria >0.3 mg/dL increase in serum creatinine within 48 hours or >1.5x increase within 7 days, after a minimum of 48 hours from HRS recovery)	binary	1 = Yes, 0 = No
1543	retreatment_terli	Retreated with terlipressin?	binary	1 = Yes, 0 = No

Nadir and Peak Serum Creatinine During Hospitalization

#	Variable	Field Label	Type	Unit
1547	nadirhospit_scr	Nadir serum creatinine during hospitalization	text	mg/dL
1550	peakhospit_scr	Peak serum creatinine during hospitalization	text	mg/dL

Renal Replacement Therapy

#	Variable	Field Label	Type	Values
1553	rrt	Renal replacement therapy?	categorical	0 = No, 1 = Yes, 2 = Need for RRT, but not a candidate
1554	rrt_modality	What was the modality of renal replacement therapy?	categorical	1 = Intermittent, 2 = Continuous
1555	rrt_continuous	Was renal replacement therapy continuous?	categorical

Hospitalization Course

#	Variable	Field Label	Type	Values
–	lt_during_hospital	Liver transplant during hospitalization?	binary	1 = Yes, 0 = No
–	slkt_during_hospital	Simultaneous liver-kidney transplant during hospitalization?	binary	1 = Yes, 0 = No
–	days_to_lt	Days from admission to liver transplant	calculated
–	hd_discharge	Hemodialysis at time of discharge?	categorical
–	disposition	Discharge disposition	categorical	1 = Home, 2 = Skilled Nursing Facility, 3 = Rehabilitation, 4 = Other facility, 5 = Death
–	days_to_discharge	Days from admission to discharge	calculated
–	lt_eval	Liver transplant evaluation status	categorical
–	lteval_listingstatus	Liver transplant listing status	categorical

Follow-Up

90-Day Follow-Up

Variable	Field Label	Type	Values
dc_death_90days	Death within 90 days of discharge?	categorical	0 = No, 1 = Yes, 2 = Lost to follow-up
dc_days_to_death	Days from discharge to death	number
dc_days_lastencounter	Days from discharge to last encounter	number
days_to_lost_to_followup	Days from discharge to lost to follow-up	number
dc_lt_90days	Liver transplant within 90 days of discharge?	categorical	0 = No, 1 = Liver transplant, 2 = Simultaneous liver-kidney transplant
dc_hd_status	Hemodialysis status at follow-up	categorical
dc_terli_use	Terlipressin re-use after discharge?	binary	1 = Yes, 0 = No
dc_aki_recurrence	AKI recurrence after discharge?	binary	1 = Yes, 0 = No
dc_aki_recurrence_eitology	Etiology of AKI recurrence	categorical

Follow-Up Lab Values

Variable	Field Label	Type	Unit
dc_scr30_value	Serum creatinine at 30 days post-discharge	text	mg/dL
dc_scr60_value	Serum creatinine at 60 days post-discharge	text	mg/dL
dc_scr90_value	Serum creatinine at 90 days post-discharge	text	mg/dL
dc_albumin	Albumin at follow-up	text	g/dL
dc_inr	INR at follow-up	text
dc_scr	Serum creatinine at follow-up	text	mg/dL
dc_sna	Serum sodium at follow-up	text	mmol/L
dc_tbili	Total bilirubin at follow-up	text	mg/dL

1-Year Follow-Up

Variable	Field Label	Type	Values
vital_status_1yr	Vital status at 1 year	categorical
hd_status_1yr	Hemodialysis status at 1 year	categorical
scr_value_1yr	Serum creatinine at 1 year	text	mg/dL
lt_status_1yr	Liver transplant status at 1 year	categorical
lt_type_1yr	Liver transplant type at 1 year	categorical
days_to_lt_1yr	Days from discharge to liver transplant	calculated
tips_1yr	TIPS within 1 year?	categorical
tips_1yr_indication	Indication for TIPS	categorical