The Liver Transplant sub-project of the HARMONY Terlipressin Registry describes transplant listing, liver transplantation, renal replacement therapy, readmission and survival through 1 year in HRS-AKI patients treated with terlipressin, using the sites’ Extended Follow-Up (EFU) REDCap form.
Cohort
Master cohort — the locked final_master_01282026.xlsx (n = 243), loaded through the shared pipeline with every standard derived variable.
EFU cohort — master patients with an EFU record in the 13 site CSVs under Extended Data Collection/Finalized Files/09SEP2026/ (222 rows; 221 join to the master — one CCF row is not a master patient, and the 22 CSF patients have no EFU file). All three tables use this cohort.
Outputs
#
Output
Cohort
Stratifier
Rows
1
Demographics Table 1
EFU cohort
efu_listingstatus
age, sex, race, etiology, prior complications, prior AKI, midodrine / octreotide, pressors, MELD 3.0 (admission, day 0), baseline / admission labs, map_day0_avg, ACLF grade, CLIF-C, ICU, extended criteria 1–4, terlipressin route, duration, albumin before / during therapy, HRS response
2
EFU summary
EFU cohort
listed_transplant (index hospitalization)
all 40 EFU outcome fields
3
EFU summary
EFU cohort
efu_listingstatus (any time ≤ 1 yr)
same, minus the stratifier
Plus a join-QC table and a cross-tabulation of the two listing definitions.
Project-specific derived variables
Variable
Definition
id_key
Normalized study ID (UPPERCASE-PREFIX-integer, YAL → YALE) used to join EFU files to the master
map_day0_avg
Mean of map_terli_day0_time0–time3 after recoding 0 (not measured) to NA
efu_*
EFU form fields (see EFU Variables); yes/no as 0/1, labs parsed with parse_number()
Pipeline
flowchart TD
A[final_master_01282026.xlsx<br/>n = 243] --> B[Source shared_pipeline.qmd]
C[13 site EFU CSVs<br/>09SEP2026, 222 rows] --> D[Normalize study IDs]
B --> E[inner_join on id_key<br/>EFU cohort n = 221]
D --> E
E --> F[map_day0_avg, numeric coercions]
F --> G[Table 1 — demographics<br/>by efu_listingstatus]
F --> H[Table 2 — EFU outcomes<br/>by listed_transplant]
F --> I[Table 3 — EFU outcomes<br/>by efu_listingstatus]
Repository Structure
Path
Description
docs/analysis.qmd
Canonical analysis — sources the shared pipeline, imports EFU data, renders Tables 1–3 with tableone::CreateTableOne() (the page shows the same output as the CSVs)
docs/efu_variables.qmd
EFU REDCap data dictionary, rendered
docs/tables/
CSV versions of the tables
EFU_DataDictionary.csv
REDCap data dictionary export for the EFU form
Code/liver request 11122025.Rmd
Legacy analyst script (Nov 2025; published to RPubs) — superseded